BPC-157: what it is, what’s been studied, and what we ship
BPC-157 is a 15-amino-acid peptide. The sequence comes from a fragment of body protection compound, a larger protein found in human gastric juice. Croatian researchers picked it apart in the early 1990s and synthesized this short version because it survives stomach acid and is easy to make in a lab.
It shows up in a lot of preclinical animal-model papers — well over a thousand on PubMed at last count, mostly out of Croatian and Asian research groups. Most of that work looks at how BPC-157 affects nitric oxide signaling, vascular endothelial growth factor, and dopaminergic systems in rats and mice. None of it has been done in human clinical trials with FDA endpoints. That gap is important and we’ll come back to it.
The sequence
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. Fifteen residues. We supply it as a sterile-filtered, lyophilized white powder, 10 mg per vial.
Quality and what’s in the box
Every batch we ship is tested by HPLC for purity (target ≥99%) and identity-confirmed by mass spectrometry. Each vial ships with a batch-specific Certificate of Analysis. Storage is straightforward: 2–8 °C for the lyophilized form, −20 °C after reconstitution with bacteriostatic water. Most labs reconstitute to 1 mg/mL or 2 mg/mL depending on the protocol.
What the published literature looks at
We don’t quote efficacy claims because none of this work has run through FDA review and most of it is in animal models. With that said, three references that show up often in the citation chain:
- Seiwerth et al. 1997 — early wound-healing work in animal models. PMID 15840402
- Sikiric et al. 2022 — review of BPC-157 in connective-tissue cell-model studies. PMID 36551977
- 2023 review — preclinical neurology research contexts. PMID 37242459
Whether any of this translates to human physiology is an open question. That’s what “research use only” actually means.
What we don’t sell
We don’t sell BPC-157 as a drug, supplement, or therapy. The peptide hasn’t been evaluated by the FDA. It is not intended to diagnose, treat, cure, prevent, or mitigate any disease. We sell it to qualified researchers and institutional labs, full stop.
Compliance
The product ships under the terms of our Research Use Only Disclaimer. By purchasing, you confirm that you’re a qualified research professional and that you’ll handle, store, and dispose of the material under appropriate laboratory practices.