MOTS-c 10MG

Description

MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the 12S rRNA region of the mitochondrial genome. First described in 2015, MOTS-c was among the earliest mitochondrially-encoded peptides identified as having activity outside the organelle, and it remains a subject of active research in the field of mitochondrial biology.

Research Context

Preclinical investigations have examined MOTS-c in rodent and cell-culture models of metabolic regulation, AMPK signaling, and glucose handling. Laboratory studies have explored its proposed role as a retrograde signaling molecule between mitochondria and the nucleus, including investigations of its activity under metabolic stress conditions. Researchers have also studied MOTS-c in models examining skeletal muscle metabolism and exercise-related signaling. The peptide is of ongoing interest within mitochondrial genetics research as one of a growing class of small open reading frame (smORF) products encoded by the mitochondrial genome.

Reconstitution & Storage

• Recommended reconstitution: 2-3 mL bacteriostatic water per 10 mg vial
• Storage: Lyophilized: 2-8°C (refrigerated), long-term -20°C. Reconstituted: 2-8°C, use within 28 days.
• Stability: Avoid freeze-thaw cycles. Protect from light.

Quality Specifications

Research Use Only Disclaimer

This product is sold strictly for laboratory and scientific research purposes. Not for human consumption, ingestion, or administration. Not intended to diagnose, treat, cure, or prevent any disease. Not approved by the FDA for any clinical use.