CJC-1295 no DAC 5MG
CJC-1295 no DAC 5MG
$50.00
CJC-1295 is a synthetic GHRH analog based on the bioactive 1-29 fragment of native human growth hormone-releasing hormone. The “No DAC” version omits the drug-affinity complex modification — meaning it clears from plasma faster in animal models. Used in protocols where extended exposure isn’t the goal.
What ships: 5MG per vial · ≥99% HPLC-verified purity · MS-confirmed identity · batch-specific Certificate of Analysis.
| Quantity | You save | Per unit |
|---|---|---|
| 3+ | 5% | $47.50 |
| 5+ | 10% | $45.00 |
| 10+ | 15% | $42.50 |
Description
CJC-1295 without DAC, also known as Modified GRF (1-29) or tetrasubstituted GRF (1-29), is a synthetic 30-amino-acid analog of the N-terminal active fragment of growth hormone-releasing hormone (GHRH). The “no DAC” designation indicates the absence of the Drug Affinity Complex modification that extends half-life through albumin binding, leaving a shorter-acting analog suited to pulsatile experimental designs.
Research Context
Preclinical investigations have studied Modified GRF (1-29) as a GHRH receptor agonist in rodent and in vitro pituitary models, with research interest centered on pulsatile growth hormone (GH) secretion dynamics. The shorter pharmacokinetic profile, relative to DAC-modified analogs, has made it a tool of interest for laboratory studies examining acute GH release kinetics and feedback regulation within the hypothalamic-pituitary axis. Researchers have also used the compound in comparative studies alongside ghrelin mimetics to examine synergistic signaling at the somatotroph level.
Reconstitution & Storage
- Recommended reconstitution: 2-3 mL bacteriostatic water per 5 mg vial
- Storage: Lyophilized: 2-8°C (refrigerated), long-term -20°C. Reconstituted: 2-8°C, use within 28 days.
- Stability: Avoid freeze-thaw cycles. Protect from light.
Quality Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥99% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Form | Lyophilized powder |
| Vial size | 5 mg |
| COA | Included with order |
Research Use Only Disclaimer
This product is sold strictly for laboratory and scientific research purposes. Not for human consumption, ingestion, or administration. Not intended to diagnose, treat, cure, or prevent any disease. Not approved by the FDA for any clinical use.
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