Tirzepatide is a synthetic peptide that activates two receptors at once: the GIP receptor and the GLP-1 receptor. Both belong to the incretin family — gut hormones that respond to nutrient intake. Until tirzepatide came along, most incretin research peptides only hit one of the two.

Eli Lilly developed it; researchers studying metabolic pathways have been using it in lab work since around 2018. The molecule is roughly 39 amino acids long with a long-chain fatty acid moiety attached via a linker, which slows down clearance in animal models.

The two receptor systems

GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) are both class B G-protein-coupled receptors. Cell-model work suggests that hitting both at the same time produces a different downstream cAMP response than hitting either one alone. That’s the question most preclinical tirzepatide papers are asking: does dual-agonism do something single-agonism doesn’t?

What we ship

Two strengths: 15 mg per vial and 30 mg per vial, both lyophilized. Purity verified by HPLC (target ≥99%). Identity confirmed by mass spectrometry. Batch-specific Certificate of Analysis with every order.

Reconstitution math

Most labs reconstitute tirzepatide with bacteriostatic water at 5–10 mg/mL for stock and dilute from there. The product page has a calculator for the math; concentration is in mg/mL and mcg/mL, with a U-100 syringe-units output for convenience. The calculator is for laboratory dilution math, not human dosing.

Selected literature

PubMed has dozens of preclinical tirzepatide papers. A few starting points:

• Coskun et al. 2018 — initial characterization of tirzepatide as a dual GIP/GLP-1 receptor agonist.
• Min et al. 2021 — comparative laboratory work on dual vs. single-receptor incretin compounds.

The references those papers cite are a good way into the deeper threads.

Compliance

Tirzepatide is supplied under our Research Use Only Disclaimer. It is not approved by the FDA for human or veterinary use, and we don’t sell it for any therapeutic purpose. By purchasing, you confirm you’re a qualified researcher.

If you’re looking for the drug version under brand names like Mounjaro or Zepbound, we don’t sell those and can’t help. Talk to a physician.

View the Tirzepatide 30mg product page → · 15mg →