KPV 10MG
KPV 10MG
$68.00
KPV is three amino acids: Lys-Pro-Val. It’s the C-terminal tail of α-MSH, the melanocyte-stimulating hormone. Researchers working on melanocortin signaling and inflammatory-pathway models use it because it’s short, cheap to synthesize, and the activity in cell-model work is reproducible across labs.
What ships: 10MG per vial · ≥99% HPLC-verified purity · MS-confirmed identity · batch-specific Certificate of Analysis.
| Quantity | You save | Per unit |
|---|---|---|
| 3+ | 5% | $64.60 |
| 5+ | 10% | $61.20 |
| 10+ | 15% | $57.80 |
Description
KPV is a tripeptide composed of lysine-proline-valine, derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone (alpha-MSH). It represents one of the smallest known peptide fragments retaining biological activity in preclinical assays, and has been studied since the 1990s as a model compound for examining anti-inflammatory signaling at the cellular level.
Research Context
Preclinical investigations have examined KPV in in vitro and rodent models of mucosal and epithelial inflammation. Research interest has centered on its activity in models of NF-kB signaling and cytokine modulation, particularly within gastrointestinal epithelial cell lines. Laboratory studies have also explored KPV in models examining peptide transport via intestinal PepT1, given its small molecular size. Investigators have used the tripeptide as a comparator in structure-activity studies of alpha-MSH-derived sequences, examining how minimal sequence length relates to retention of anti-inflammatory activity in cell-based assays.
Reconstitution & Storage
- Recommended reconstitution: 2-3 mL bacteriostatic water per 10 mg vial
- Storage: Lyophilized: 2-8°C (refrigerated), long-term -20°C. Reconstituted: 2-8°C, use within 28 days.
- Stability: Avoid freeze-thaw cycles. Protect from light.
Quality Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥99% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Form | Lyophilized powder |
| Vial size | 10 mg |
| COA | Included with order |
Research Use Only Disclaimer
This product is sold strictly for laboratory and scientific research purposes. Not for human consumption, ingestion, or administration. Not intended to diagnose, treat, cure, or prevent any disease. Not approved by the FDA for any clinical use.
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