Tesamorelin 5MG
Tesamorelin 5MG
$37.00
Tesamorelin is a synthetic GHRH analog. The native sequence has been modified at the N-terminus with a hexenoyl group, which slows down the dipeptidyl peptidase-4 (DPP-4) cleavage that breaks down native GHRH in plasma. That modification makes tesamorelin useful in protocols where the native peptide degrades too fast to be measurable.
What ships: 5MG per vial · ≥99% HPLC-verified purity · MS-confirmed identity · batch-specific Certificate of Analysis.
| Quantity | You save | Per unit |
|---|---|---|
| 3+ | 5% | $35.15 |
| 5+ | 10% | $33.30 |
| 10+ | 15% | $31.45 |
Description
Tesamorelin is a synthetic 44-amino-acid analog of human growth hormone-releasing hormone (GHRH), modified at the N-terminus with a trans-3-hexenoic acid group that confers resistance to dipeptidyl peptidase-IV (DPP-IV) degradation. The molecule has been a subject of research interest since the early 2000s as a stabilized GHRH analog.
Research Context
Preclinical investigations have examined tesamorelin as a GHRH receptor agonist in rodent and in vitro pituitary models. Laboratory research has studied the compound’s role in stimulating pulsatile growth hormone secretion and downstream IGF-1 generation. Researchers have used tesamorelin in models examining the somatotropic axis, with particular research interest in adipose tissue biology and visceral fat distribution in preclinical metabolic studies. The DPP-IV-resistant modification has made it a useful comparator in structure-activity studies of GHRH analogs, where researchers examine how N-terminal modifications relate to plasma stability and receptor activity.
Reconstitution & Storage
- Recommended reconstitution: 2 mL bacteriostatic water per 5 mg vial
- Storage: Lyophilized: 2-8°C (refrigerated), long-term -20°C. Reconstituted: 2-8°C, use within 28 days.
- Stability: Avoid freeze-thaw cycles. Protect from light.
Quality Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥99% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Form | Lyophilized powder |
| Vial size | 5 mg |
| COA | Included with order |
Research Use Only Disclaimer
This product is sold strictly for laboratory and scientific research purposes. Not for human consumption, ingestion, or administration. Not intended to diagnose, treat, cure, or prevent any disease. Not approved by the FDA for any clinical use.
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