TB-500 (Thymosin Beta-4) 10MG
TB-500 (Thymosin Beta-4) 10MG
$128.00
TB-500 is a synthetic peptide fragment based on the active region of Thymosin Beta-4. The full Thymosin Beta-4 protein is 43 amino acids long; TB-500 covers the section that interacts with G-actin in cell-based studies. Most of the published work is in animal models — wound-healing assays, cardiac tissue research, tendon-cell papers.
What ships: 10MG per vial · ≥99% HPLC-verified purity · MS-confirmed identity · batch-specific Certificate of Analysis.
| Quantity | You save | Per unit |
|---|---|---|
| 3+ | 5% | $121.60 |
| 5+ | 10% | $115.20 |
| 10+ | 15% | $108.80 |
Description
TB-500 is a synthetic peptide corresponding to a fragment of thymosin beta-4, a 43-amino-acid actin-sequestering peptide originally isolated from bovine thymic tissue in the early 1980s. Thymosin beta-4 is the most abundant member of the beta-thymosin family in many mammalian cell types, and the TB-500 designation has been used across preclinical research workflows examining beta-thymosin biology.
Research Context
Preclinical investigations have examined thymosin beta-4 in laboratory models of actin sequestration, cell migration, and angiogenesis. Researchers have used the peptide in in vitro studies of endothelial-cell tube formation, fibroblast motility, and wound-margin migration in scratch assays. Laboratory work has also explored beta-thymosin family peptides in rodent cardiac and dermal repair models. The compound is widely cited within the actin cytoskeleton research literature as a model G-actin-sequestering molecule, and continues to be of interest in structure-function studies examining how short, intrinsically disordered peptides interact with cytoskeletal proteins.
Reconstitution & Storage
- Recommended reconstitution: 2-3 mL bacteriostatic water per 10 mg vial
- Storage: Lyophilized: 2-8°C (refrigerated), long-term -20°C. Reconstituted: 2-8°C, use within 28 days.
- Stability: Avoid freeze-thaw cycles. Protect from light.
Quality Specifications
| Parameter | Specification |
|---|---|
| Purity | ≥99% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Form | Lyophilized powder |
| Vial size | 10 mg |
| COA | Included with order |
Research Use Only Disclaimer
This product is sold strictly for laboratory and scientific research purposes. Not for human consumption, ingestion, or administration. Not intended to diagnose, treat, cure, or prevent any disease. Not approved by the FDA for any clinical use.
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